"On the Numerical Architecture of Nonribosomal Undecapeptides: A Structural Alignment of Ciclosporin and Lucas-Fibonacci Progressions" by Stefan A. Geier et al.
On the Numerical Architecture of Nonribosomal Undecapeptides: A Structural Alignment of Ciclosporin and Lucas-Fibonacci Progressions - A First Look by Stefan A. Geier*, Caroline Geier, Stephanie Geier, Constantin Geier, Katharina Geier, Nora Blättermann-Goldstein, and Michèle Geier-Noehl** Institute for Structuralistic Theory of Sciences Simssee (ISTS), Gerhart-Hauptmann-Straße 6, 83071 Haidholzen, Germany; and Ludwig-Maximilians-Universität Munich, Germany ** Dermatologische Klinik der Landeshauptstadt und der Ludwig-Maximilians-Universität LMU München, Thalkirchner Straße 48, 80337 Munich, Germany * Correspondence: wissenschaftstheorie.simssee.1@gmail.com Abstract Ciclosporin (Cyclosporin A) is a clinically vital, lipophilic cyclic undecapeptide synthesized via nonribosomal peptide synthetase (NRPS) pathways. Beyond its established pharmacological role as a calcineurin inhibitor, its primary sequence and architectural topology exhibit striking mathematical alignments. This paper expl...
