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Does SAMHD1 approximate FIBONACCI numbers, or LUCAS numbers?

Does SAMHD1 Approximate Fibonacci, and Lucas Numbers?

The human protein SAMHD1 is composed of 626 amino acids (according to UniProt: Q9Y3Z3 · SAMH1_HUMAN). Interestingly, 610 is the 15th Fibonacci number, and this is very close to the length of SAMHD1. The relative difference is only about 2.6%, meaning SAMHD1 approximates the 15th Fibonacci number to approximately 97.4% accuracy.

This numerical proximity between a key biological molecule and a well-known mathematical sequence may offer an interesting basis for further discussion and exploration.

Sincerely,
Stefan Geier, Haidholzen

Keywords: SAMHD1 (Sterile Alpha Motif and Histidine-Aspartate Domain-Containing Protein 1), interferon, HIV, virus, SAMHD1-dependent resistance, oncology


Reference:
1. UniProt: Q9Y3Z3 · SAMH1_HUMAN
2. Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT. SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. Nat Med. 2012 Nov;18(11):1682–1687. doi: 10.1038/nm.2964. PMID: 22972397; PMCID: PMC3828732.





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