Dengue virus (DENV) and FIBONACCI- and LUCAS-numbers - A first look by Stefan Geier

Dengue virus (DENV) and FIBONACCI- and LUCAS-numbers -
A first look
by Stefan Geier

"DENV contains 10 723 nucleotides in a single-strand positive RNA genome, which encodes a large polyprotein precursor of 3 391 amino-acid residues." (Vivek Dhar Dwivedi et al.)

The 21th FIBONACCI-number is 10 946.
The 17th LUCAS-number is 3571 (a LUCAS prime).
The genome length of  DENV fits the 21th FIBONACCI-number with 97.96 % precision.
The proteom length of DENV fits the 17th LUCAS-number 3 571 (a LUCAS prime) with 94.96 % precision.

Therefore, we conclude that the Dengue virus (DENV) fits our considerations on FIBONACCI- and LUCAS-numbers and GEIER's equations.

The polyprotein of DENV comprises three structural proteins (C, prM and E) and (five or) seven nonstructural proteins (NS1, NS2A, NS2B, NS3, NS4A, NS4B and NS5). 3 is a LUCAS- and a FIBONACCI-number; 5 is a FIBONACCI-number; 7 is a LUCAS-number. This corroborates the above.

Reference:
Genomics, proteomics and evolution of dengue virus
by
Vivek Dhar Dwivedi,
Indra Prasad Tripathi,
Ramesh Chandra Tripathi,
Shiv Bharadwaj,
Sarad Kumar Mishra.
Briefings in Functional Genomics, Volume 16, Issue 4, July 2017, Pages 217–227, https://doi.org/10.1093/bfgp/elw040
"
Diagrammatic representation of the DENV genome [38]. (A) 5ʹ and 3ʹ UTRs and the open reading frame of the DENV indicating structural proteins, C, prM, E, and nonstructural proteins, NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5 [38]. The location of the complementary sequences 5ʹ–3ʹCS (solid lines) and 5ʹ–3ʹUAR (dashed lines) also have been shown. (B) Predicted secondary structure of the 5ʹ terminal region of the viral genome [38]. Structural elements that are located at the 5ʹ end are shown as stem loop A (SLA), stem loop B (SLB), oligo (U) track spacer, translation initiator AUG, capsid region hairpin (cHP) and the 5ʹCS element. (C) Representation of predicted RNA elements at the 3ʹ UTR of the DENV genome. The predicted secondary structures of the three defined domains are shown: DI comprising variable region (VR), DII comprising DB structures (DB1 and DB2) and DIII consisting conserved sequence CS1 and 3ʹSL. In addition, the location and sequence of each of the conserved elements corresponding to RCS2, CS2, 3ʹCS and 3ʹUAR are also indicated [38].
Figure 1. Diagrammatic representation of the DENV genome [38]. (A) 5ʹ and 3ʹ UTRs and the open reading frame of the DENV indicating structural proteins, C, prM, E, and nonstructural proteins, NS1, NS2A, NS2B, NS3, NS4A, NS4B, NS5 [38]. The location of the complementary sequences 5ʹ–3ʹCS (solid lines) and 5ʹ–3ʹUAR (dashed lines) also have been shown. (B) Predicted secondary structure of the 5ʹ terminal region of the viral genome [38]. Structural elements that are located at the 5ʹ end are shown as stem loop A (SLA), stem loop B (SLB), oligo (U) track spacer, translation initiator AUG, capsid region hairpin (cHP) and the 5ʹCS element. (C) Representation of predicted RNA elements at the 3ʹ UTR of the DENV genome. The predicted secondary structures of the three defined domains are shown: DI comprising variable region (VR), DII comprising DB structures (DB1 and DB2) and DIII consisting conserved sequence CS1 and 3ʹSL. In addition, the location and sequence of each of the conserved elements corresponding to RCS2, CS2, 3ʹCS and 3ʹUAR are also indicated [38]."

See: 
16.06.2026: DLF 10:08 Uhr Sprechstunde Live
Ebola, Dengue, West-Nil:
Risiken tropischer Infektionskrankheiten in Europa
Prof. Dr. med. Micha Loebermann, Facharzt für Innere Medizin, Infektiologie und Tropenmedizin, Leiter der Klinik und Poliklinik für Infektiologie, Nephrologie, Endokrinologie und Tropenmedizin an der Uniklinik Rostock
Am Mikrofon: Christina Sartori
„Es war eine schreckliche Zeit“
Herwig Schober, ein von einer Dengue-Fieber Betroffener berichtet.

Please, compare with TBEV:
https://humanistischebetrachtungen1.blogspot.com/2026/06/tick-borne-encephalitis-virus-tbev-and.html
References:
Frey S, Essbauer S, Zöller G, Klempa B, Weidmann M, Dobler G, Pfeffer M. Complete Genome Sequence of Tick-Borne Encephalitis Virus Strain A104 Isolated from a Yellow-Necked Mouse (Apodemus flavicollis) in Austria. Genome Announc. 2013 Aug 8;1(4):e00564-13. doi: 10.1128/genomeA.00564-13. PMID: 23929473; PMCID: PMC3738889.
Geier Stefan et al. "GEIER's Equations" and "GEIER's Φ(e) ↔ Φ(α) Equilibrium Programme" with FIBONACCI/LUCAS extensions (GEIER's Equations Part 2.1). ResearchGate, February 2026, DOI:
10.13140/RG.2.2.33185.67689.



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