"Omega-5 gliadin (Tri a 19) genome length and FIBONACCI- or LUCAS-numbers: a 98% fit! A first look" by Stefan Geier, Michele Geier-Noehl et al.

Omega-5 gliadin (Tri a 19) genome length and FIBONACCI- or LUCAS-numbers: a 98% fit! - A first look

by Stefan Geier, Michele Geier-Noehl et al.
Gerhart-Hauptmann-Straße 6, 83071 Haidholzen

Omega-5 gliadin (Tri a 19) is a major wheat allergen encoded at the Gli-1 locus on the short arm of chromosome 1B. The coding sequence length of the gene is typically about 1,344 base pairs (bp), translating to a 439-amino-acid protein with a molecular mass of roughly 65 kDa.

Genomic & Protein Specifications
Gene Coding Length: mean 1,344 bp ("The ω-5a gene consists of 1,413 bp and has an ORF throughout the entire 1317 bp coding region. The nucleotide and deduced amino acid sequences are shown in Fig. 2. The nucleotide sequence of the ω-5b gene - which has 1275 bp - is almost identical to that of ω-5a gene except that the repetitive domain is 138 bp shorter."*):
1344/nearest FIBONACCI- or LUCAS-number = 1344/L15 = 1344/1364 = 98.5%, with L15 the 15th LUCAS-number = Phi^15.
This is compatible with GEIER's equations and corroborates GEIER's programme**.

Protein Length: 439 amino acids
Molecular Mass: ≈ 65 kDa
Chromosome Location: Short arm of chromosome 1B (specifically at the Gli-B1 locus)
Amino Acid Composition: 68-73% glutamine and proline; lacks cysteine and methionine

Key Characteristics
Tri a 19 is the primary trigger for Wheat-Dependent Exercise-Induced Anaphylaxis (WDEIA) in adults and immediate hypersensitivity reactions in children. It is distinct from other omega gliadins (like omega-1,2 gliadins) by its specific SRL- type N-terminal sequence and its unique repetition of FPQQQ and QQIPQQ motifs.

#FOBI2026


*Matsuo, H., Kohno, K. and Morita, E. (2005), Molecular cloning, recombinant expression and IgE-binding epitope of ω-5 gliadin, a major allergen in wheat-dependent exercise-induced anaphylaxis. The FEBS Journal, 272: 4431-4438. https://doi.org/10.1111/j.1742-4658.2005.04858.x
**St. Geier et al. "GEIER's Equations" and "GEIER's Φ(e) ↔ Φ(α) Equilibrium Programme" with FIBONACCI/LUCAS extensions (GEIER's Equations Part 2.1). ResearchGate, February 2026, DOI:

10.13140/RG.2.2.33185.67689.

...

Wikipedia, today: Gliadin is a class of proteins present in wheat and several other cereals within the grass genus Triticum. It is the main toxic fraction of gluten for people with gluten-related disorders.

Date	12 February 2019
Source	Own work
Author	BallenaBlanca